What is the BioGears Physiology Engine?
The BioGears Physiology Engine (or just BioGears) is an open source, comprehensive, extensible human physiology simulation software released under the Apache 2.0 license. BioGears drives medical education, research, and training technologies. BioGears enables accurate, consistent, and credible physiology simulation and may be used as a standalone application or integrated with simulators, sensor interfaces, and other computational models.
Download NowWhat can the BioGears Physiology Engine do?
BioGears has a long list of capabilities and features including:
- BioGears includes mathematical models for a wide range of systems, medical interfaces, and substances for real-time computation and retrieval of accurate physiology state.
- The common data model includes standard inputs, outputs, units, conversions, and naming conventions that make model additions and product integration quick and easy.
- Support for the large and growing community of users. Explore showcase scenarios on this website, collaborate with us on GitHub, and use the tutorials to guide BioGears integration.
- A full-featured API, SDK, code-based documentation, and tutorial examples make BioGears easy to understand and use. Rigorous validation methods ensure credible model output.
Community Focused
BioGearsEngine.com includes all the documentation you will need to use and modify BioGears. We support and engage our community of users through GitHub, conferences, and access to code-based documentation. Upcoming events are announced here on biogearsengine.com. We hope you can visit us at one of the upcoming events!
Work With Us!
BioGears is developed and maintained by Applied Research Associates, Inc. (ARA). We are always looking for research partners and sponsors! The ARA team is interested in talking to you about extensions and applications of the BioGears Phsyiology Engine and new health, medicine, and biomedical engineering projects.
Explore a Scenario Explore More Scenarios
Soldier Multi-Trauma
The Soldier Multi-Trauma Showcase Scenario simulates the injuries that a Combat Medic or other caregiver may encounter on the battlefield. This scenario highlights the ability of the BioGears physiology engine to simulate multiple insults occurring simultaneously. We have incorporated a tension pneumothorax with a massive hemorrhage. The tension pneumothorax is itself a combinatory insult, affecting both the respiratory and cardiovascular systems. Combining the tension pneumothorax with the blood loss from the hemorrhage pushes and eventually exceeds the limits of the homeostatic control mechanisms.
See the Validation Matrix for more details about the narrative and validation of the combined insult and intervention physiologic effects.
Scenario Timeline
Environment Exposure
The Environment Exposure Showcase Scenario simulates the physiology of an adult woman who is exposed to cold weather long enough to develop hypothermia. This scenario highlights the ability of the BioGears physiology engine to simulate physiology when the body is exposed to an abnormal environment.
See the Validation Matrix for more details about the narrative and validation of the combined insult and intervention physiologic effects.
Scenario Timeline
Asthma Attack
The Asthma Attack Showcase Scenario simulates physiology during an asthma attack and after administration of a beta-agonist. This scenario highlights the ability of the BioGears physiology engine to simulate asthma and inhaled-drug administration.
See the Validation Matrix for more details about the narrative and validation of the combined insult and intervention physiologic effects.
Scenario Timeline
Heat Stroke
The heat stroke scenario simulates the body's temperature regulation system. This scenario highlights the ability of the BioGears physiology engine to simulate the energy exchange between the human body and the environment.
See the Validation Matrix for more details about the narrative and validation of the combined insult and intervention physiologic effects.
Scenario Timeline
Sepsis
The sepsis scenario highlights the biogears inflammation/infection model and subsequent treatments. Patient reactions were validated with the University of Washington Advanced Modular Manikin project. During the onset of severe septic infection originating in the gut the patient sees symptoms in line with SIRS: increased core temperature, elevated white blood cell count and an elevated respiration rate. Treatments in line with best practice patient management. BioGears supports antibiotics, fluid infusions, and norepinephrine administration.
Scenario Timeline
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Whats Next?
Get started with your new BioGears Physiology Engine project, take a look at the documentation, and interact with our growing community over at GitHub.
