BioGears Systems

The open source BioGears physiology engine is a whole body simulation comprised of accurate system-level models. The system-level mathematical models provide real-time retrieval of accurate physiology state, and can power your immersive medical training technologies and research.

Current Systems

Anesthesia Machine

The Anesthesia Machine Model is a generic representation of mechanical ventilation and inhaled agent administration.

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Blood Chemistry

The blood chemistry system provides clinically relevant values that accurately represent quantities of substances in the bloodstream.

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Cardiovascular

The cardiovascular system models compute hemodynamics and include insults, interventions and assessments such as heart failure, CPR, and EKG.

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Drugs

The drugs system calculates the diffusion, clearance, and effects for each drug in the system to form a complete PK/PD model.

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Endocrine

The endocrine system maintains homeostasis through feedback mechanisms.

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Energy Balance

The Energy system provides a methodology for both thermal and metabolic regulation.

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Environment

The environment system modifies ambient values and thermal properties.

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Gastrointestinal

The Gastrointestinal system models the ingestion of food and subsequent transport to the Cardiovascular system.

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Hepatic

The hepatic system provides the starting point for modeling the many functions of the liver.

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Inhaler

The BioGears Inhaler Model is a generic representation of a pressurized metered dose inhaler (pMDI).

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Nervous

The nervous system represents the central nervous system (CNS) and peripheral nervous system (PNS).

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Patient

Patient variability is provided via a set of parameters used to define aspects of the simulated human.

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Renal

The Renal system is responsible for filtering blood.

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Respiratory

The respiratory system models compute gas exchange and include insults, interventions and assessments such as asthma attack, intubation, and pulmonary function tests.

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Systems

The BioGears Engine consists of a fully customizable collection of physiologic systems.

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Tissue

The tissue system is responsible for the metabolic production and consumption of substances, as well as gas exchange.

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